jwh-018 powder for sale
jwh-018 powder for sale , Fatalities associated with synthetic cannabinoids abuse have been reported. Shanks et al. reported three cases where fatalities were associated with synthetic cannabinoid use. In case one, a 57-year old man died due to use of JWH-018. The cardiac blood showed 199 ng/mL of JWH-018 along with other prescription drugs. In the second case a 52-year old year man died who showed 19.6 ng/mL of JWH-018 and 68.3 ng/mL of JWH-073 in cardiac blood. In the third case a 29-year old man died who showed only the presence of JWH-018 (83.3 ng/mL) in the cardiac blood but no other drug [33]. Labay et al. recently reviewed cases where death was related to use of synthetic cannabinoids.
The authors identified six deaths related to abuse of JWH-018 (postmortem blood levels: 0.11–0.65 ng/mL), six deaths related to abuse of JWH-122, six deaths related to abuse of JWH-210, one each associated with abuse of JWH-175 and JWH-250, respectively. In addition, two fatalities associated with abuse of XLR-11 and nine fatalities associated with abuse of AM-2201 (postmortem blood levels: 0.13–17.0 ng/mL) were also reported [34]. Patton et al. also reported death of a 23-year old man due to AM-2201 overdose. The metabolite of AM-2201 was detected in the postmortem blood [35].
Death due to use of synthetic cannabinoids (S)-methyl-2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3-methylbutanoate (5F-AMB), a new synthetic cannabinoid first reported in Japan in early 2014, has also been reported. The concentration of 5F-AMB was only 0.3 ng/mL. However, the authors concluded that the death was accidental [36]. Shanks et al. described a death associated with use of a new synthetic cannabinoid ADB-4-fluorobenzyl-1H-indazole-3-carboxamide (FUBINACA). In this drug, 1-amino-3,3-deimethoxy-1-oxobutane-2yl (ABD) group is linked with FUBINACA base at the amide group. The concentration of this relatively new synthetic cannabinoid in the postmortem blood was 7.3 ng/mL. However, a small amount of THC (1.1 ng/mL) and its metabolite THC-COOH (4.7 ng/mL) was also detected in the postmortem blood using LC-MS/MS [37].
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